Cannabidiol (CBD) derived from the hemp plant is used for various therapeutic and medical purposes. It is effective for mitigating the symptoms of various common day ailments. Health and wellness products formulated using it as the active ingredient are popular among users due to their lack of side-effects. Also, the onset time of these products varies depending on the method you use as this influences how the body absorbs cannabidiol. The purpose of this article is to investigate how CBD is absorbed in different methods of consumption.
The method of using cannabidiol (CBD) health and wellness products depends on your requirement. For instance, if you want quick relief from chronic pain, then inhaling CBD vapors is ideal as this method has the quickest onset time. Also, applying cannabidiol topical products like creams, balms, and ointments gives quick localized relief. Oral consumption has the longest onset time.
CBD when ingested increases serotonin levels by influencing 5-HT1A receptors, and it reduces pain by stimulating TRPV1 or vanilloid receptors. Likewise, cannabidiol affects GABA receptors and increases the calming effect of GABA, which is a neurotransmitter.
In this method, drops of CBD tincture are placed under the tongue and held there for 30 to 60 seconds. Cannabidiol enters the bloodstream through the sublingual gland; due to this, the onset time is fast. The advantage of sublingual consumption of CBD is that the bioavailability is high as it bypasses the first-pass metabolism.
The most common method of consuming CBD is orally in the form of pills, oils, and edibles. Here, the onset time is longest because cannabidiol must pass through the digestive system to be absorbed into the bloodstream. Also, its bioavailability is low. Due to this, the total amount of cannabidiol available for the ECS is reduced, resulting in reduced therapeutic effects.
Inhaling CBD has the fastest onset time and the highest bioavailability. This is because cannabidiol enters the systemic circulation through the lungs. Due to this, it also bypasses the first-pass metabolism of the liver.
When you apply CBD topical products on the skin, cannabidiol does not enter the bloodstream. Due to this, their therapeutic effects are localized, and the bioavailability of CBD will be extremely low.
On a final note, for CBD therapy, methods of administering cannabidiol are chosen such that you get maximum health benefits.
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